One step closer to a cure for dementia 97



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Earlier this week a new discovery has lead to scientists believing they are one step closer to curing dementia. A team from the Catholic University of Leuven published their findings in the Stem Cells Reports journal. They were able to repair diseased brain cells taken from patients with a common form of dementia for which their is no cure.

They identified a gene variant that prevents neurons from forming properly and managed to correct it through genetic engineering. This was an impressive discovery but what was greater is that they could also alter the gene with a compound that inhibited a chemical response for the gene mutation and believe that this finding could be the first step towards a “dementia pill”.

The researchers will now work to better understand what goes wrong in these mutated cells, as well as identify precise molecular targets that could then be used for drug screens.

Currently dementia is one of the most prevalent diseases in developed countries and has one of the biggest impacts on quality of life as we age. Earlier this year it was found by another group of researchers that the five lifestyle factors that affect dementia onset are; getting regular exercise, give up smoking, reaching and maintaining a healthy body weight, eating a mediterranean diet and keeping alcohol consumption low.

They believed that by living by these five rules, the annual dementia diagnosis could reduce by up to 80,000.

Finding a cure – as simple as a pill would be incredible. It would bring loved ones back to us and possibly lead to more stable prevention. But, the drug isn’t formulated yet and we don’t know when it will be so the big question is, would you ever consider being a part in the clinical trials?

Starts at 60 Writers

The Starts at 60 writers team seek out interesting topics and write them especially for you.

  1. Vitamin D has been shown to improve a number of brain disorders, including dementia and its most severe form, Alzheimer’s disease,1 the latter of which now affects an estimated 5.2 million Americans.

  2. Yes I would most definitely try it .

  3. I would normally say yes and jump, however my friend with dementia many years ago was put on an approved drug to halt the progression of the disease. It had severe side effects for her bowel and eventually after a few years where the disease had obviously not been halted they decided it wasn’t working and the known side effects were worsening, she stopped taking it. Since then research has shown this well known drug, which would have made millions for the company, not to be worthy of all the published hype they spread, and that it was not stopping the disease in its tracks or even slowing it. So, I have become a bit more sceptical, because she did rush in and still now suffers from the damage it did to her bowel function. Unfortunately, everything seems to have side effects and sometimes big Pharma don’t tell the truth. So I would be a bit more wary now, which is hard if you are desperate like she was.

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